Cancer, Heart Research Today Ahead of Science Airlock Installation

Cancer, Heart Research Today Ahead of Science Airlock Installation

A U.S. Cygnus and a Russian Soyuz spacecraft are pictured docked to the station as it orbited above the Pacific Ocean.
A U.S. Cygnus and a Russian Soyuz spacecraft are pictured docked to the station as it orbited above the Pacific Ocean.

The Expedition 64 crew is busy this week with a full slate of life science to promote healthier humans on and off the Earth. Cancer and heart research took precedence today alongside muscle and rodent studies for unique therapeutic insights on the International Space Station.

The microgravity environment on the station enables the production of high-quality protein crystals that are imaged using a microscope for the purpose of improving drug development. The Monoclonal Antibodies study taking place today will use the observations to improve medical cancer treatments and the space manufacturing process.

Engineered heart tissue samples are being observed this week for the Cardinal Heart investigation. NASA Flight Engineer Kate Rubins is leading that experiment to understand why weightlessness seems to induce cell and tissue abnormalities similar to heart conditions on Earth. Results may help doctors understand and predict cardiovascular risks for Earthlings and astronauts.

More muscle work was on the research schedule today as the crew continued with measurements and ultrasound scans today. The Myotones investigation monitors how microgravity changes muscles and tendons in an astronaut’s body to provide countermeasures for crews in space and therapies for patients on Earth.

Rodents are also being studied this month for insights into tissue and bone loss as well as eye changes caused by living in space. One study will study explore how genetic modifications affect bone and tissue regeneration. The second will look at new treatments for space-caused and Earthbound eye problems.

Robotics controllers are preparing to remove a new science airlock delivered to the station last week inside the SpaceX Cargo Dragon’s unpressurized trunk. Using the Canadarm2 robotic arm, the NanoRacks Bishop airlock will be attached to the Tranquility module this weekend ramping up commercial research opportunities in space.

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Mark Garcia

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Space Biology on Station Seeks to Improve Human Health

Space Biology on Station Seeks to Improve Human Health

Expedition 64 Flight Engineer Soichi Noguchi gives a
Expedition 64 Flight Engineer Soichi Noguchi gives a “thumbs up” inside the seven-windowed cupola, the International Space Station’s “window to the world.”

Space biology was the dominant research theme aboard the International Space Station today. The Expedition 64 crew explored heart cells, muscles and more to understand how microgravity impacts the human body.

The Cardinal Heart study has been under way all week with the crew observing engineered heart tissue samples through a microscope in Japan’s Kibo laboratory module. The samples are being processed inside the Life Sciences Glovebox to help researchers understand and treat abnormal heart cells and tissues that can lead to disease both on Earth and in space.

The lack of gravity aboard the space station means astronauts exert less energy when moving around the orbiting lab resulting in muscle atrophy. Daily exercise offsets this loss and keeps crew members healthy and strong during long term missions and prepares them for the return to Earth after months of living in space.

The Myotones study taking place today seeks to understand the biochemical properties of muscles exposed to weightlessness. Analysis of ultrasound scans and blood samples taken from crew members could give scientists insights into muscle conditions caused by lack of movement and aging.

Organ transplants are critical on Earth especially with demand exceeding supply. Doctors are exploring generating cell growth in three dimensions and creating artificial organs in space since Earth’s gravity limits this growth. The new Space Organogenesis study ongoing this month uses the space station to enable 3D cell growth to promote regenerative technology and someday support patients on Earth who need transplants.

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Mark Garcia

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More Heart Research as Next Cygnus Cargo Mission Booked

More Heart Research as Next Cygnus Cargo Mission Booked

Expedition 64 Flight Engineer Victor Glover reviews research procedures for an experiment that could accelerate the development of advanced therapies that target cancer cells.
Expedition 64 Flight Engineer Victor Glover reviews research procedures for an experiment that could accelerate the development of advanced therapies that target cancer cells.

The Expedition 64 crew continues exploring how microgravity affects the heart to improve health for humans on and off the Earth. Northrop Grumman has booked its next Cygnus resupply mission to the International Space Station for early next year.

NASA Flight Engineers Kate Rubins and Michael Hopkins partnered up today for the Cardinal Heart study to learn how to treat aging and weakening heart cells. Hopkins peered at heart tissue samples through a microscope while Rubins serviced those samples in the Kibo laboratory module’s Life Sciences Glovebox.

Blood sample collections were on the morning schedule for Flight Engineer Victor Glover as he took glucose measurements for the Vascular Aging study. He then moved on to a space manufacturing study that seeks to vastly improve the production and quality of optic fibers.

On the maintenance front, JAXA astronaut Soichi Noguchi serviced U.S. spacesuits throughout Tuesday scrubbing cooling loops in the U.S. Quest airlock. NASA Flight Engineer Shannon Walker continued installing and outfitting the station’s new bathroom, the Universal Waste Management System, in the Tranquility module.

Commander Sergey Ryzhikov worked during the morning replacing components inside the Zvezda service module’s treadmill then moved on to cargo transfers inside the Progress 76 resupply ship. Flight Engineer Sergey Kud-Sverchkov swapped fuel bottles inside the Combustion Integrated Rack research facility before configuring life support and communications hardware

Northrop Grumman has announced Feb. 20 for the launch of its Cygnus space freighter to the space station with several tons of cargo to resupply the crew. Cygnus will take a two-day trip to the orbiting lab before it is captured with the Canadarm2 robotic arm and installed to the Unity module where it will stay for two months.

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Mark Garcia

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Heart Research and New Toilet Installation on Station Today

Heart Research and New Toilet Installation on Station Today

Expedition 64 Flight Engineer Kate Rubins works inside the Life Sciences Glovebox conducting research for the Cardinal Heart study.
Expedition 64 Flight Engineer Kate Rubins works inside the Life Sciences Glovebox conducting research for the Cardinal Heart study.

Cardiac research and orbital plumbing were the Monday highlights for the Expedition 64 crew aboard the International Space Station.

Flight Engineer Kate Rubins peered through a microscope at heart tissue samples today for the Cardinal Heart study. The microgravity study may provide new insights and advanced therapies for heart conditions on Earth and in space.

For the Vascular Echo experiment today, Flight Engineer Victor Glover strapped on a Doppler probe to his right leg to scan his femoral artery during a light exercise session. The cardiovascular study, running since March 2015 on the orbiting lab, is looking at how living in space stiffens the arteries.

A brand new, advanced toilet, delivered Oct. 5 on the 14th Cygnus resupply mission, is being installed on the space station today. NASA astronauts Michael Hopkins and Shannon Walker put on their plumber caps today to assemble and install the Universal Waste Management System in the Tranquility module. The station’s second space bathroom was designed to be better integrated with water systems, as well as smaller, lighter, easier to use and more comfortable.

In the Russian segment of the station, Commander Sergey Ryzhikov and Flight Engineer Sergey Kud-Sverchkov focused on cargo transfers and inventory updates. The duo is packing the Progress 76 resupply ship with trash and discarded gear for its departure from the Pirs docking compartment in February.

Early Saturday morning, an unexplained power glitch resulted in a loss of power to some International Space Station systems that are operated by one of eight power channels for the complex (4B channel). The crew was never in any danger, and the affected systems were repowered in a short period of time by one of the other station’s power channels (4A).

As of Monday morning, all impacted station systems are operating normally while flight controllers in Mission Control review data to try to assess the cause of the problem and a forward plan of remedial action.

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Mark Garcia

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Cancer and Heart Studies, Spacesuit Swaps Aboard Station Today

Cancer and Heart Studies, Spacesuit Swaps Aboard Station Today

Four Expedition 64 crew members are pictured relaxing after a meal at the end of the work day inside the Unity module.
Four Expedition 64 crew members are pictured relaxing after a meal at the end of the work day inside the Unity module.

Life science continues ramping up aboard the International Space Station as the Expedition 64 crew explores cancer therapies and heart conditions.

NASA Flight Engineers Kate Rubins and Victor Glover set up research hardware to create high quality antibody crystals Thursday morning for a new cancer study. The space medical research could accelerate the development of advanced therapies on Earth that target cancer cells.

Rubins then spent the afternoon servicing samples for the Cardinal Heart study that observes microgravity’s affect on aging and weakening heart muscles. Glover participated in ultrasound eye exams with fellow Flight Engineers Shannon Walker and Soichi Noguchi.

NASA astronaut Michael Hopkins, with assistance from Noguchi, spent the day swapping U.S. spacesuits inside the SpaceX Cargo Dragon resupply ship today. One spacesuit was launched to the station on Sunday ready for operations another will return to Earth next month for maintenance.

Station Commander Sergey Ryzhikov configured gear inside the Poisk mini-research module before working on the Zarya module’s ventilation system. Flight Engineer Sergey Kud-Sverchkov swapped fuel bottles inside the Combustion Integrated Rack that enables safe research into fuel and flame studies.

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Mark Garcia

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